BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetProbable nicotinate-nucleotide adenylyltransferase
LigandBDBM88962
Substrate/Competitorn/a
IC50 4250±n/a nM
Citation PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article
 
Probable nicotinate-nucleotide adenylyltransferase
Name:Probable nicotinate-nucleotide adenylyltransferase
Synonyms:NADD_STAAN | hypothetical protein SA1422 | nadD
Type:Enzyme Catalytic Domain
Mol. Mass.:22100.53
Organism:Staphylococcus aureus subsp. aureus N315
Description:gi_15927174
Residue:189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMI
QMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIE
YLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENY
IKGEGLYEH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM88962
n/a
NameBDBM88962
Synonyms:(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate | (6R,7R)-7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(carboxymethoxyimino)-1-oxoethyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate | (6R,7R)-7-[[(2E)-2-(2-aminothiazol-4-yl)-2-(carboxymethyloximino)acetyl]amino]-8-keto-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate | (6R,7R)-7-[[(2E)-2-(2-azanyl-1,3-thiazol-4-yl)-2-(2-hydroxy-2-oxoethyloxyimino)ethanoyl]amino]-3-ethenyl-8-oxidanylidene-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate | CEFIXIME | CEFIXIME TRIHYDRATE | MLS001076665 | SMR000469225 | cid_56642849
TypeSmall organic molecule
Emp. Form.C16H15N5O7S2
Mol. Mass.453.45
SMILESNc1nc(cs1)C(=N/OCC(O)=O)\C(=O)N[C@H]1[C@H]2SCC(C=C)=C(N2C1=O)C(O)=O |c:23|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: