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TargetHepatocyte nuclear factor 4-alpha
LigandBDBM34683
Substrate/Competitorn/a
IC50 3454±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization PubChem Bioassay(2012)[AID]
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Hepatocyte nuclear factor 4-alpha
Name:Hepatocyte nuclear factor 4-alpha
Synonyms:HNF4 | HNF4A | HNF4A_HUMAN | NR2A1 | TCF14 | hepatocyte nuclear factor 4-alpha isoform b
Type:PROTEIN
Mol. Mass.:52790.24
Organism:Homo sapiens (Human)
Description:ChEMBL_606516
Residue:474
Sequence:
MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC
AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC
FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK
IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK
DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK
GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL
FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW
PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
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  Blast E-value cutoff:
BDBM34683
n/a
NameBDBM34683
Synonyms:3-(phenylcarbonyl)benzo[g][1]benzofuran-4,5-dione | 3-benzoylbenzo[g][1]benzofuran-4,5-dione | 3-benzoylbenzo[g]benzofuran-4,5-dione | 3-benzoylbenzo[g]benzofuran-4,5-quinone | 3-benzoylnaphtho[1,2-b]furan-4,5-dione | MLS000532159 | SMR000137100 | cid_1895639
TypeSmall organic molecule
Emp. Form.C19H10O4
Mol. Mass.302.2803
SMILESO=C(c1coc-2c1C(=O)C(=O)c1ccccc-21)c1ccccc1
Structure
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