| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte nuclear factor 4-alpha |
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| Ligand | BDBM43818 |
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| Substrate/Competitor | n/a |
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| IC50 | 3883±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Hepatocyte nuclear factor 4-alpha |
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| Name: | Hepatocyte nuclear factor 4-alpha |
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| Synonyms: | HNF4 | HNF4A | HNF4A_HUMAN | NR2A1 | TCF14 | hepatocyte nuclear factor 4-alpha isoform b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52790.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_606516 |
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| Residue: | 474 |
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| Sequence: | MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC
AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC
FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK
IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK
DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK
GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL
FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW
PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
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| BDBM43818 |
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| n/a |
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| Name | BDBM43818 |
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| Synonyms: | (2Z)-3-ethyl-2-[(E)-3-(3-ethyl-5-phenyl-1,3-benzoxazol-3-ium-2-yl)prop-2-enylidene]-5-phenyl-1,3-benzoxazole;ethyl sulfate | MLS-0285976.0001 | cid_10864994 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H29N2O2 |
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| Mol. Mass. | 485.595 |
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| SMILES | CCN1\C(Oc2ccc(cc12)-c1ccccc1)=C\C=C\c1oc2ccc(cc2[n+]1CC)-c1ccccc1 |
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| Structure | 
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