| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte nuclear factor 4-alpha |
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| Ligand | BDBM94561 |
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| Substrate/Competitor | n/a |
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| IC50 | 970±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Hepatocyte nuclear factor 4-alpha |
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| Name: | Hepatocyte nuclear factor 4-alpha |
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| Synonyms: | HNF4 | HNF4A | HNF4A_HUMAN | NR2A1 | TCF14 | hepatocyte nuclear factor 4-alpha isoform b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52790.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_606516 |
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| Residue: | 474 |
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| Sequence: | MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC
AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC
FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK
IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK
DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK
GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL
FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW
PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
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| BDBM94561 |
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| n/a |
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| Name | BDBM94561 |
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| Synonyms: | 2-(2-fluorophenyl)-2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl]-N-pentylacetamide | 2-(2-fluorophenyl)-2-[3-(furan-2-yl)-2-oxidanylidene-quinoxalin-1-yl]-N-pentyl-ethanamide | 2-(2-fluorophenyl)-2-[3-(furan-2-yl)-2-oxoquinoxalin-1-yl]-N-pentylacetamide | MLS003674170 | N-amyl-2-(2-fluorophenyl)-2-[3-(2-furyl)-2-keto-quinoxalin-1-yl]acetamide | SMR002353638 | cid_53383152 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24FN3O3 |
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| Mol. Mass. | 433.4748 |
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| SMILES | CCCCCNC(=O)C(c1ccccc1F)n1c2ccccc2nc(-c2ccco2)c1=O |
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| Structure | 
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