| Reaction Details |
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 | Report a problem with these data |
| Target | ADP-ribosylation factor GTPase-activating protein 1 |
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| Ligand | BDBM32341 |
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| Substrate/Competitor | n/a |
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| IC50 | 81720±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| ADP-ribosylation factor GTPase-activating protein 1 |
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| Name: | ADP-ribosylation factor GTPase-activating protein 1 |
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| Synonyms: | ARFG1_RAT | Arf1gap | Arfgap1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45436.38 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_21489979 |
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| Residue: | 415 |
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| Sequence: | MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
SVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAE
GKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQE
NRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKA
SELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAED
TSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSS
DSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
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| BDBM32341 |
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| n/a |
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| Name | BDBM32341 |
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| Synonyms: | 5-(3-Chloro-phenyl)-furan-2-carboxylic acid (4-morpholin-4-ylmethyl-phenyl)-amide | 5-(3-chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide | 5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide | 5-(3-chlorophenyl)-N-[4-(morpholinomethyl)phenyl]-2-furamide | MLS000557592 | SMR000148508 | cid_2011756 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21ClN2O3 |
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| Mol. Mass. | 396.867 |
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| SMILES | Clc1cccc(c1)-c1ccc(o1)C(=O)Nc1ccc(CN2CCOCC2)cc1 |
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| Structure | 
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