| Reaction Details |
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 | Report a problem with these data |
| Target | ADP-ribosylation factor GTPase-activating protein 1 |
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| Ligand | BDBM94657 |
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| Substrate/Competitor | n/a |
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| IC50 | 5041±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| ADP-ribosylation factor GTPase-activating protein 1 |
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| Name: | ADP-ribosylation factor GTPase-activating protein 1 |
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| Synonyms: | ARFG1_RAT | Arf1gap | Arfgap1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45436.38 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_21489979 |
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| Residue: | 415 |
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| Sequence: | MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
SVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAE
GKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQE
NRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKA
SELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAED
TSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSS
DSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
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| BDBM94657 |
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| n/a |
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| Name | BDBM94657 |
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| Synonyms: | 5-amino-N-(5-chloro-2-methoxy-phenyl)-1-[2-keto-2-(m-anisidino)ethyl]triazole-4-carboxamide | 5-amino-N-(5-chloro-2-methoxyphenyl)-1-[2-(3-methoxyanilino)-2-oxoethyl]-4-triazolecarboxamide | 5-amino-N-(5-chloro-2-methoxyphenyl)-1-[2-(3-methoxyanilino)-2-oxoethyl]triazole-4-carboxamide | 5-azanyl-N-(5-chloranyl-2-methoxy-phenyl)-1-[2-[(3-methoxyphenyl)amino]-2-oxidanylidene-ethyl]-1,2,3-triazole-4-carboxamide | MLS001116615 | SMR000630064 | cid_20923743 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19ClN6O4 |
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| Mol. Mass. | 430.845 |
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| SMILES | COc1cccc(NC(=O)Cn2nnc(C(=O)Nc3cc(Cl)ccc3OC)c2N)c1 |
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| Structure | 
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