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TargetADP-ribosylation factor GTPase-activating protein 1
LigandBDBM95229
Substrate/Competitorn/a
IC50>18306±n/a nM
Citation PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article
 
ADP-ribosylation factor GTPase-activating protein 1
Name:ADP-ribosylation factor GTPase-activating protein 1
Synonyms:ARFG1_RAT | Arf1gap | Arfgap1
Type:Enzyme Catalytic Domain
Mol. Mass.:45436.38
Organism:Rattus norvegicus
Description:gi_21489979
Residue:415
Sequence:
MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
SVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAE
GKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQE
NRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKA
SELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAED
TSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSS
DSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
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  Blast E-value cutoff:
BDBM95229
n/a
NameBDBM95229
Synonyms:MLS001234985 | N-(3-chlorophenyl)-2-(7-methyl-4-oxidanylidene-pyrido[1,2-a][1,3,5]triazin-2-yl)sulfanyl-ethanamide | N-(3-chlorophenyl)-2-(7-methyl-4-oxopyrido[1,2-a][1,3,5]triazin-2-yl)sulfanylacetamide | N-(3-chlorophenyl)-2-[(4-keto-7-methyl-pyrido[1,2-a][1,3,5]triazin-2-yl)thio]acetamide | N-(3-chlorophenyl)-2-[(7-methyl-4-oxo-2-pyrido[1,2-a][1,3,5]triazinyl)thio]acetamide | SMR000810925 | cid_7259073
TypeSmall organic molecule
Emp. Form.C16H13ClN4O2S
Mol. Mass.360.818
SMILESCc1ccc2nc(SCC(=O)Nc3cccc(Cl)c3)nc(=O)n2c1
Structure
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