| Reaction Details |
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 | Report a problem with these data |
| Target | ADP-ribosylation factor GTPase-activating protein 1 |
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| Ligand | BDBM95233 |
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| Substrate/Competitor | n/a |
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| IC50 | 44878±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| ADP-ribosylation factor GTPase-activating protein 1 |
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| Name: | ADP-ribosylation factor GTPase-activating protein 1 |
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| Synonyms: | ARFG1_RAT | Arf1gap | Arfgap1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45436.38 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_21489979 |
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| Residue: | 415 |
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| Sequence: | MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
SVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAE
GKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQE
NRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKA
SELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAED
TSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSS
DSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
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| BDBM95233 |
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| n/a |
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| Name | BDBM95233 |
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| Synonyms: | 5-methoxy-3-methyl-2-benzofurancarboxylic acid [2-(3,5-dimethyl-1-piperidinyl)-2-oxoethyl] ester | 5-methoxy-3-methyl-coumarilic acid [2-(3,5-dimethylpiperidino)-2-keto-ethyl] ester | MLS001079362 | SMR000716221 | [2-(3,5-dimethylpiperidin-1-yl)-2-oxidanylidene-ethyl] 5-methoxy-3-methyl-1-benzofuran-2-carboxylate | [2-(3,5-dimethylpiperidin-1-yl)-2-oxoethyl] 5-methoxy-3-methyl-1-benzofuran-2-carboxylate | cid_16265426 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25NO5 |
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| Mol. Mass. | 359.4162 |
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| SMILES | COc1ccc2oc(C(=O)OCC(=O)N3CC(C)CC(C)C3)c(C)c2c1 |
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| Structure | 
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