| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 5 group A member 2 |
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| Ligand | BDBM95608 |
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| Substrate/Competitor | n/a |
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| IC50 | 2491±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Nuclear receptor subfamily 5 group A member 2 |
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| Name: | Nuclear receptor subfamily 5 group A member 2 |
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| Synonyms: | Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2 |
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| Type: | Nuclear Hormone Receptor |
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| Mol. Mass.: | 61341.37 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 541 |
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| Sequence: | MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQG
QMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRY
TCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQ
QKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPF
VTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPAS
IPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWA
RSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQA
GATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAA
LLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKR
A
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| BDBM95608 |
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| n/a |
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| Name | BDBM95608 |
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| Synonyms: | 2-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-oxidanylidene-pyrazin-2-yl]sulfanyl-N-(4-ethoxyphenyl)ethanamide | 2-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-ethoxyphenyl)acetamide | 2-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-keto-pyrazin-2-yl]thio]-N-p-phenetyl-acetamide | 2-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-oxo-2-pyrazinyl]thio]-N-(4-ethoxyphenyl)acetamide | MLS001236962 | SMR000812488 | cid_18579402 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N3O5S |
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| Mol. Mass. | 439.484 |
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| SMILES | CCOc1ccc(NC(=O)CSc2nccn(-c3ccc4OCCOc4c3)c2=O)cc1 |
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| Structure | 
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