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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Methionine--tRNA ligase | ||
| Ligand | BDBM95856 | ||
| Substrate/Competitor | n/a | ||
| IC50 | 974±n/a nM | ||
| Citation |  PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) PubChem Bioassay(2013)[AID] | ||
| More Info.: | Get all data from this article | ||
| Methionine--tRNA ligase | |||
| Name: | Methionine--tRNA ligase | ||
| Synonyms: | methionyl-tRNA synthetase | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 86905.45 | ||
| Organism: | Trypanosoma brucei brucei strain 927/4 GUTat10.1 | ||
| Description: | gi_71746704 | ||
| Residue: | 773 | ||
| Sequence: |
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| BDBM95856 | |||
| n/a | |||
| Name | BDBM95856 | ||
| Synonyms: | (2S,3R,12bS)-2-((4-chlorobenzyl)(methyl)amino)-3-((S)-1-hydroxyethyl)-1,2,3,6,7,12b-hexahydroindolo[2,3-a]quinolizin-4(12H)-one | (2S,3R,12bS)-2-[(4-chlorobenzyl)-methyl-amino]-3-[(1S)-1-hydroxyethyl]-2,3,6,7,12,12b-hexahydro-1H-pyrido[2,1-a]-carbolin-4-one | (2S,3R,12bS)-2-[(4-chlorophenyl)methyl-methyl-amino]-3-[(1S)-1-oxidanylethyl]-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one | (2S,3R,12bS)-2-[(4-chlorophenyl)methyl-methylamino]-3-[(1S)-1-hydroxyethyl]-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one | MLS002920944 | SMR001798409 | cid_46902354 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H28ClN3O2 | ||
| Mol. Mass. | 437.962 | ||
| SMILES | C[C@H](O)[C@H]1[C@H](C[C@@H]2N(CCc3c2[nH]c2ccccc32)C1=O)N(C)Cc1ccc(Cl)cc1 | ||
| Structure | 
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