| Reaction Details |
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 | Report a problem with these data |
| Target | Tumor necrosis factor receptor superfamily member 10B |
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| Ligand | BDBM49291 |
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| Substrate/Competitor | n/a |
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| EC50 | 9480±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for a small molecule Caspase-8 TRAIL sensitizers in a luminescence panel assay PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Tumor necrosis factor receptor superfamily member 10B |
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| Name: | Tumor necrosis factor receptor superfamily member 10B |
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| Synonyms: | DR5 | KILLER | TNFRSF10B | TR10B_HUMAN | TRAILR2 | TRICK2 | ZTNFR9 | tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens] |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47869.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_224494019 |
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| Residue: | 440 |
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| Sequence: | MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
HLLSSGKFMYLEGNADSAMS
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| BDBM49291 |
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| n/a |
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| Name | BDBM49291 |
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| Synonyms: | MLS000061602 | N-[4-(diethylamino)phenyl]-2-furamide | N-[4-(diethylamino)phenyl]-2-furancarboxamide | N-[4-(diethylamino)phenyl]furan-2-carboxamide | SMR000069932 | cid_675057 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N2O2 |
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| Mol. Mass. | 258.3156 |
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| SMILES | CCN(CC)c1ccc(NC(=O)c2ccco2)cc1 |
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| Structure | 
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