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TargetLow molecular weight phosphotyrosine protein phosphatase
LigandBDBM94977
Substrate/Competitorn/a
IC50 11600±n/a nM
Citation PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay(2013)[AID]
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Low molecular weight phosphotyrosine protein phosphatase
Name:Low molecular weight phosphotyrosine protein phosphatase
Synonyms:3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:n/a
Mol. Mass.:18042.81
Organism:Homo sapiens (Human)
Description:P24666
Residue:158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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BDBM94977
n/a
NameBDBM94977
Synonyms:4-N-(3,4-dimethoxyphenyl)-2-N-(thiophen-2-ylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine | MLS003123011 | N4-(3,4-dimethoxyphenyl)-N2-(thiophen-2-ylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine | SMR001278085 | [4-(3,4-dimethoxyanilino)thieno[3,2-d]pyrimidin-2-yl]-(2-thenyl)amine | cid_49789153
TypeSmall organic molecule
Emp. Form.C19H18N4O2S2
Mol. Mass.398.502
SMILESCOc1ccc(Nc2nc(NCc3cccs3)nc3ccsc23)cc1OC
Structure
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