Reaction Details |
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Target | Low molecular weight phosphotyrosine protein phosphatase |
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Ligand | BDBM94977 |
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Substrate/Competitor | n/a |
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IC50 | 11600±n/a nM |
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Citation | PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article |
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Low molecular weight phosphotyrosine protein phosphatase |
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Name: | Low molecular weight phosphotyrosine protein phosphatase |
Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
Type: | n/a |
Mol. Mass.: | 18042.81 |
Organism: | Homo sapiens (Human) |
Description: | P24666 |
Residue: | 158 |
Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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BDBM94977 |
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n/a |
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Name | BDBM94977 |
Synonyms: | 4-N-(3,4-dimethoxyphenyl)-2-N-(thiophen-2-ylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine | MLS003123011 | N4-(3,4-dimethoxyphenyl)-N2-(thiophen-2-ylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine | SMR001278085 | [4-(3,4-dimethoxyanilino)thieno[3,2-d]pyrimidin-2-yl]-(2-thenyl)amine | cid_49789153 |
Type | Small organic molecule |
Emp. Form. | C19H18N4O2S2 |
Mol. Mass. | 398.502 |
SMILES | COc1ccc(Nc2nc(NCc3cccs3)nc3ccsc23)cc1OC |
Structure |
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