| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 22 |
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| Ligand | BDBM51767 |
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| Substrate/Competitor | n/a |
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| IC50 | >80000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in a fluorescence-based, Lymphoid Phosphatase (PTPN22, LYP-1) selectivity Assay PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Tyrosine-protein phosphatase non-receptor type 22 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 22 |
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| Synonyms: | 3.1.3.48 | Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP | LyP | Lymphoid phosphatase | Lymphoid phosphatase (Lyp) | PEP | PEST-domain phosphatase | PTN22_HUMAN | PTPN22 | PTPN8 | Tyrosine-protein phosphatase non-receptor type 22 (LYP) | tyrosine-protein phosphatase non-receptor type 22 isoform 1 |
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| Type: | n/a |
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| Mol. Mass.: | 91712.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y2R2 |
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| Residue: | 807 |
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| Sequence: | MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY
KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY
SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS
ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI
DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK
HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE
ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL
LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC
FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW
PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES
AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS
EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET
YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS
SSFLNFGFANRFSKPKGPRNPPPTWNI
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| BDBM51767 |
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| n/a |
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| Name | BDBM51767 |
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| Synonyms: | 2-[(4-methyl-2-quinolyl)thio]-N-[5-(p-tolyl)-1,2,4-thiadiazol-3-yl]acetamide | MLS000586735 | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-(4-methylquinolin-2-yl)sulfanyl-ethanamide | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-(4-methylquinolin-2-yl)sulfanylacetamide | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(4-methyl-2-quinolinyl)thio]acetamide | N-[5-(4-methylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(4-methylquinolin-2-yl)thio]acetamide | SMR000208666 | cid_4256434 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N4OS2 |
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| Mol. Mass. | 406.524 |
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| SMILES | Cc1ccc(cc1)-c1nc(NC(=O)CSc2cc(C)c3ccccc3n2)ns1 |
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| Structure | 
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