| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fructose-bisphosphate aldolase |
|---|
| Ligand | BDBM96145 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | >1110±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Fructose-bisphosphate aldolase |
|---|
| Name: | Fructose-bisphosphate aldolase |
|---|
| Synonyms: | ALF_MYCTU | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-1,6-bisphosphate aldolase (FBA) | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba | fba |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36539.01 |
|---|
| Organism: | Mycobacterium tuberculosis (strain H37Rv) |
|---|
| Description: | P9WQA3 |
|---|
| Residue: | 344 |
|---|
| Sequence: | MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFG
SGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKG
GNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKL
YTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGL
PADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLK
VDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
|
|
|
|---|
| BDBM96145 |
|---|
| n/a |
|---|
| Name | BDBM96145 |
|---|
| Synonyms: | (+)-trans-ethyl-khellactone | (9S,10R)-10-ethoxy-8,8-dimethyl-9-oxidanyl-9,10-dihydropyrano[2,3-f]chromen-2-one | (9S,10R)-10-ethoxy-9-hydroxy-8,8-dimethyl-9,10-dihydropyrano[2,3-f][1]benzopyran-2-one | (9S,10R)-10-ethoxy-9-hydroxy-8,8-dimethyl-9,10-dihydropyrano[2,3-f]chromen-2-one | MLS002472917 | SMR001397028 | cid_44144312 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18O5 |
|---|
| Mol. Mass. | 290.3111 |
|---|
| SMILES | CCO[C@H]1[C@H](O)C(C)(C)Oc2ccc3ccc(=O)oc3c12 |
|---|
| Structure | 
|
|---|
Search and Browse
