| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
|---|
| Ligand | BDBM96271 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 29742±n/a nM |
|---|
| Citation |  PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| RecBCD enzyme subunit RecD |
|---|
| Name: | RecBCD enzyme subunit RecD |
|---|
| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 66906.68 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130723 |
|---|
| Residue: | 608 |
|---|
| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
|
|
|
|---|
| BDBM96271 |
|---|
| n/a |
|---|
| Name | BDBM96271 |
|---|
| Synonyms: | 1-ethyl-6-fluoranyl-7-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-4-oxidanylidene-N-prop-2-enyl-quinoline-3-carboxamide | 1-ethyl-6-fluoro-7-[4-(furan-2-carbonyl)piperazin-1-yl]-4-oxo-N-prop-2-enylquinoline-3-carboxamide | 1-ethyl-6-fluoro-7-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-4-oxo-N-prop-2-enyl-3-quinolinecarboxamide | MLS001075284 | N-allyl-1-ethyl-6-fluoro-7-[4-(2-furoyl)piperazino]-4-keto-quinoline-3-carboxamide | SMR000646372 | cid_1894659 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H25FN4O4 |
|---|
| Mol. Mass. | 452.4781 |
|---|
| SMILES | CCn1cc(C(=O)NCC=C)c(=O)c2cc(F)c(cc12)N1CCN(CC1)C(=O)c1ccco1 |
|---|
| Structure | 
|
|---|
Search and Browse
