Ki Summary

Reaction Details

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Target

Trace amine-associated receptor 1

Ligand

BDBM96614

Substrate/Competitor

n/a

IC50

1027±n/a nM

Citation

PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay(2013)[AID]

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Trace amine-associated receptor 1

Name:

Trace amine-associated receptor 1

Synonyms:

Type:

PROTEIN

Mol. Mass.:

39107.47

Organism:

Homo sapiens (Human)

Description:

ChEMBL_792734

Residue:

339

Sequence:

MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID
RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG
GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG
ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN
PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS

BDBM96614

n/a

Name

BDBM96614

Synonyms:

2-(3,4-Dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-propionylamino-propionic acid ethyl ester | 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-(1-oxopropylamino)propanoic acid ethyl ester | 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-propionamido-propionic acid ethyl ester | MLS000554893 | SMR000147010 | cid_3590464 | ethyl 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-trifluoro-2-(propanoylamino)propanoate | ethyl 2-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3,3-tris(fluoranyl)-2-(propanoylamino)propanoate

Type

Small organic molecule

Emp. Form.

C17H21F3N2O3

Mol. Mass.

358.3554

SMILES

CCOC(=O)C(NC(=O)CC)(N1CCc2ccccc2C1)C(F)(F)F

Structure