| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage colony-stimulating factor 1 |
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| Ligand | BDBM97728 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Competition Immunoassay |
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| pH | 7.5±0 |
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| IC50 | 1±n/a nM |
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| Citation |  Illig, CR; Ballentine, SK; Chen, J; DesJarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent US8481564 Publication Date 7/9/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Macrophage colony-stimulating factor 1 |
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| Name: | Macrophage colony-stimulating factor 1 |
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| Synonyms: | CSF1_MOUSE | Csf1 | Csfm | Macrophage colony-stimulating factor 1 (CSF-1) |
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| Type: | Protein |
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| Mol. Mass.: | 60631.84 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P07141 |
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| Residue: | 552 |
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| Sequence: | MTARGAAGRCPSSTWLGSRLLLVCLLMSRSIAKEVSEHCSHMIGNGHLKVLQQLIDSQME
TSCQIAFEFVDQEQLDDPVCYLKKAFFLVQDIIDETMRFKDNTPNANATERLQELSNNLN
SCFTKDYEEQNKACVRTFHETPLQLLEKIKNFFNETKNLLEKDWNIFTKNCNNSFAKCSS
RDVVTKPDCNCLYPKATPSSDPASASPHQPPAPSMAPLAGLAWDDSQRTEGSSLLPSELP
LRIEDPGSAKQRPPRSTCQTLESTEQPNHGDRLTEDSQPHPSAGGPVPGVEDILESSLGT
NWVLEEASGEASEGFLTQEAKFSPSTPVGGSIQAETDRPRALSASPFPKSTEDQKPVDIT
DRPLTEVNPMRPIGQTQNNTPEKTDGTSTLREDHQEPGSPHIATPNPQRVSNSATPVAQL
LLPKSHSWGIVLPLGELEGKRSTRDRRSPAELEGGSASEGAARPVARFNSIPLTDTGHVE
QHEGSSDPQIPESVFHLLVPGIILVLLTVGGLLFYKWKWRSHRDPQTLDSSVGRPEDSSL
TQDEDRQVELPV
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| BDBM97728 |
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| n/a |
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| Name | BDBM97728 |
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| Synonyms: | US8481564, 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N5O3 |
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| Mol. Mass. | 431.487 |
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| SMILES | CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1nc(c[nH]1)C#N)C1CC(=O)NC(=O)C1 |c:5| |
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| Structure | 
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