| Reaction Details |
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 | Report a problem with these data |
| Target | Probable nicotinate-nucleotide adenylyltransferase |
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| Ligand | BDBM98138 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | NaMNAT HPLC Enzyme Assay |
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| pH | 7.5±0 |
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| Temperature | 273.15±0 K |
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| IC50 | 10100±0.0 nM |
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| Citation |  Moro, WB; Yang, Z; Kane, TA; Zhou, Q; Harville, S; Brouillette, CG; Brouillette, WJ SAR studies for a new class of antibacterial NAD biosynthesis inhibitors. J Comb Chem11:617-25 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Inhibition_Run data, Solution Info, Assay Method |
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| Probable nicotinate-nucleotide adenylyltransferase |
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| Name: | Probable nicotinate-nucleotide adenylyltransferase |
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| Synonyms: | BAMEG_4595 | Deamido-NAD(+) diphosphorylase | Deamido-NAD(+) pyrophosphorylase | NADD_BACAC | Nicotinate mononucleotide adenylyltransferase | Nicotinate-nucleotide adenylyltransferase | Nicotinate-nucleotide adenylyltransferase (NadD) | Nicotinic acid mononucleotide adenylyltransferase (NaMNAT) | nadD |
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| Type: | Enzyme |
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| Mol. Mass.: | 21955.08 |
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| Organism: | Bacillus anthracis |
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| Description: | C3L5T6 |
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| Residue: | 189 |
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| Sequence: | MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQML
ELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIE
ALLDLVTFVGVARPGYKLRTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVY
IERNGLYES
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| BDBM98138 |
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| n/a |
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| Name | BDBM98138 |
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| Synonyms: | 1-[4-[(4-methoxyphenyl)sulfonylamino]phenyl]-3-(4-nitrophenyl)urea | Compound ID 7{1,17} |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N4O6S |
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| Mol. Mass. | 442.445 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)Nc1ccc(NC(=O)Nc2ccc(cc2)[N+]([O-])=O)cc1 |
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| Structure | 
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