| Reaction Details |
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 | Report a problem with these data |
| Target | Glutaminyl-peptide cyclotransferase |
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| Ligand | BDBM98185 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Spectrophotometic Assay |
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| Ki | 149±n/a nM |
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| IC50 | 882±n/a nM |
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| Citation |  Heiser, U; Ramsbeck, D; Sommer, R; Meyer, A; Hoffmann, T; Boehme, L; Demuth, H Inhibitors US Patent US8486940 Publication Date 7/16/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutaminyl-peptide cyclotransferase |
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| Name: | Glutaminyl-peptide cyclotransferase |
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| Synonyms: | Glutaminyl Cyclase | Glutaminyl cyclase (QC) | Glutaminyl-peptide cyclotransferase | Glutaminyl-peptide cyclotransferase precursor (QC) | Glutaminyl-tRNA cyclotransferase | Glutamyl cyclase (QC) | QPCT | QPCT_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 40877.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16769 |
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| Residue: | 361 |
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| Sequence: | MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAWPEEKNYHQPAILNSSALRQIAEGT
SISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSF
SNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLS
LKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHG
MDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYG
GVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLH
L
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| BDBM98185 |
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| n/a |
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| Name | BDBM98185 |
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| Synonyms: | US8486940, 60 | US9650362, 60 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18N4O |
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| Mol. Mass. | 354.4045 |
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| SMILES | O=C1NCC(N1c1ccn2ccnc2c1)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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