Reaction Details |
| Report a problem with these data |
Target | Serine protease 1 |
---|
Ligand | BDBM50110015 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Enzyme Assay |
---|
Temperature | 297.15±0 K |
---|
Ki | 290±0.0 nM |
---|
Citation | Stuerzebecher, J; Steinmetzer, T; Schweinitz, A Urokinase inhibitors, production and use thereof US Patent US8476306 Publication Date 7/2/2013 |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Serine protease 1 |
---|
Name: | Serine protease 1 |
Synonyms: | PTRYI | Prss1 | RATPTRYI | TRY1_RAT | Trp1 | Try1 | Tryp1 | Trypsin |
Type: | Protein |
Mol. Mass.: | 25951.67 |
Organism: | Rattus norvegicus |
Description: | P00762 |
Residue: | 246 |
Sequence: | MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVS
AAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLN
ARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEIT
SSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQ
DTIAAN
|
|
|
BDBM50110015 |
---|
n/a |
---|
Name | BDBM50110015 |
Synonyms: | CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}GLYCINAMIDE | N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hydroxy-2-phenylmethanesulfonylamino-propionamide | US8476306, 6.1 | US8476306, 6.2 |
Type | Small organic molecule |
Emp. Form. | C20H25N5O5S |
Mol. Mass. | 447.508 |
SMILES | NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 |
Structure |
|