Reaction Details |
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Target | Serine protease 1 |
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Ligand | BDBM98583 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Enzyme Assay |
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Temperature | 297.15±0 K |
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Ki | 13±0.0 nM |
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Citation | Stuerzebecher, J; Steinmetzer, T; Schweinitz, A Urokinase inhibitors, production and use thereof US Patent US8476306 Publication Date 7/2/2013 |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Serine protease 1 |
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Name: | Serine protease 1 |
Synonyms: | PTRYI | Prss1 | RATPTRYI | TRY1_RAT | Trp1 | Try1 | Tryp1 | Trypsin |
Type: | Protein |
Mol. Mass.: | 25951.67 |
Organism: | Rattus norvegicus |
Description: | P00762 |
Residue: | 246 |
Sequence: | MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVS
AAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLN
ARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEIT
SSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQ
DTIAAN
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BDBM98583 |
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n/a |
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Name | BDBM98583 |
Synonyms: | 4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methylamino]-1-methyl-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]sulfamoylmethyl]benzoic acid | US8476306, 6.8 |
Type | Small organic molecule |
Emp. Form. | C22H27N5O7S |
Mol. Mass. | 505.544 |
SMILES | C[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)Cc1ccc(cc1)C(O)=O)C(=O)NCc1ccc(cc1)C(N)=N |
Structure |
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