Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM99926 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Radioligand Binding Assay | ||
| pH | 7.5±0 | ||
| Ki | 1±0.0 nM | ||
| Citation |  Manning, DD; Cioffi, CL 5-HT3 receptor modulators, methods of making, and use thereof US Patent US8501729 Publication Date 8/6/2013 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
| ||
| BDBM99926 | |||
| n/a | |||
| Name | BDBM99926 | ||
| Synonyms: | US8501729, 21 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H17BrN4O | ||
| Mol. Mass. | 361.236 | ||
| SMILES | Brc1cc2[nH][nH]c3cn([C@H]4CN5CCC4CC5)c(=O)c(c1)c23 |r,wU:9.8,(-3.18,-5.01,;-1.85,-4.23,;-.51,-5,;.82,-4.23,;2.29,-4.71,;3.18,-3.32,;2.16,-1.92,;2.16,-.38,;.82,.39,;.82,1.93,;-.51,2.7,;-.51,4.24,;.82,5.01,;2.16,4.24,;2.16,2.7,;.56,2.7,;1.33,3.97,;-.51,-.38,;-1.85,.39,;-.51,-1.92,;-1.85,-2.69,;.82,-2.69,)| | ||
| Structure | 
| ||