Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM99928 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Binding Assay | ||
pH | 7.5±0 | ||
Ki | 4±0.0 nM | ||
Citation | Manning, DD; Cioffi, CL 5-HT3 receptor modulators, methods of making, and use thereof US Patent US8501729 Publication Date 8/6/2013 | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
Type: | Protein | ||
Mol. Mass.: | 55283.27 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P46098 | ||
Residue: | 478 | ||
Sequence: |
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BDBM99928 | |||
n/a | |||
Name | BDBM99928 | ||
Synonyms: | US8501729, 23 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H20N4O | ||
Mol. Mass. | 296.3669 | ||
SMILES | O=C1N(CCc2n[nH]c3cccc1c23)[C@@H]1CN2CCC1CC2 |r,wD:14.16,(-2.66,-.09,;-1.17,-.49,;-.45,.87,;1.04,1.16,;2.28,.16,;2.33,-1.46,;3.53,-2.43,;2.98,-3.87,;1.44,-3.79,;.35,-4.87,;-1.14,-4.48,;-1.54,-2.99,;-.45,-1.9,;1.04,-2.3,;-1.22,2.21,;-2.76,2.21,;-3.53,3.54,;-2.76,4.87,;-1.22,4.87,;-.45,3.54,;-1.8,2.82,;-2.19,4.31,)| | ||
Structure |