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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM99930 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Radioligand Binding Assay | ||
| pH | 7.5±0 | ||
| Ki | 1±0.0 nM | ||
| Citation |  Manning, DD; Cioffi, CL 5-HT3 receptor modulators, methods of making, and use thereof US Patent US8501729 Publication Date 8/6/2013 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
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| BDBM99930 | |||
| n/a | |||
| Name | BDBM99930 | ||
| Synonyms: | US8501729, 25 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H24N4O | ||
| Mol. Mass. | 324.4201 | ||
| SMILES | CCn1nc2CCN([C@@H]3CN4CCC3CC4)C(=O)c3cccc1c23 |r,wD:8.7,(3.2,-5.89,;1.71,-5.49,;1.31,-4.01,;2.22,-2.76,;1.31,-1.52,;1.74,.04,;.87,1.32,;-.67,1.43,;-1.06,2.92,;-2.55,3.32,;-2.95,4.8,;-1.86,5.89,;-.37,5.49,;.02,4.01,;-1.46,3.66,;-1.46,5.2,;-1.71,.3,;-3.2,.7,;-1.48,-1.22,;-2.82,-1.99,;-2.82,-3.53,;-1.48,-4.3,;-.15,-3.53,;-.15,-1.99,)| | ||
| Structure | 
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