Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM99931 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Binding Assay | ||
pH | 7.5±0 | ||
Ki | 2±0.0 nM | ||
Citation | Manning, DD; Cioffi, CL 5-HT3 receptor modulators, methods of making, and use thereof US Patent US8501729 Publication Date 8/6/2013 | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
Type: | Protein | ||
Mol. Mass.: | 55283.27 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P46098 | ||
Residue: | 478 | ||
Sequence: |
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BDBM99931 | |||
n/a | |||
Name | BDBM99931 | ||
Synonyms: | US8501729, 26 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H26N4O | ||
Mol. Mass. | 338.4466 | ||
SMILES | CC(C)n1nc2CCN([C@@H]3CN4CCC3CC4)C(=O)c3cccc1c23 |r,wD:9.8,(3.2,-5.55,;1.71,-5.15,;.62,-6.24,;1.31,-3.66,;2.22,-2.42,;1.31,-1.17,;1.74,.39,;.87,1.66,;-.67,1.78,;-1.06,3.26,;-2.55,3.66,;-2.95,5.15,;-1.86,6.24,;-.37,5.84,;.02,4.35,;-1.46,4.01,;-1.46,5.55,;-1.71,.65,;-3.2,1.05,;-1.48,-.88,;-2.82,-1.65,;-2.82,-3.19,;-1.48,-3.96,;-.15,-3.19,;-.15,-1.65,)| | ||
Structure |