| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM100012 |
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| Substrate/Competitor | n/a |
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| EC50 | 97538±n/a nM |
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| Citation |  PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM100012 |
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| n/a |
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| Name | BDBM100012 |
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| Synonyms: | 1'-(ethoxycarbonyl)-1-methyl-9-oxo-8,9-dihydrospiro[furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid | 1'-carbethoxy-9-keto-1-methyl-spiro[8H-furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid | 1'-ethoxycarbonyl-1-methyl-9-oxidanylidene-spiro[8H-furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid | 1'-ethoxycarbonyl-1-methyl-9-oxo-2-spiro[8H-furo[3,2-f][1]benzopyran-7,4'-piperidine]carboxylic acid | 1'-ethoxycarbonyl-1-methyl-9-oxospiro[8H-furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid | MLS000093697 | SMR000029315 | cid_3236756 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21NO7 |
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| Mol. Mass. | 387.3832 |
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| SMILES | CCOC(=O)N1CCC2(CC1)CC(=O)c1c(O2)ccc2oc(C(O)=O)c(C)c12 |
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| Structure | 
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