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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Kallikrein-7 | ||
| Ligand | BDBM100014 | ||
| Substrate/Competitor | n/a | ||
| EC50 | 20785±n/a nM | ||
| Citation |  PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] | ||
| More Info.: | Get all data from this article | ||
| Kallikrein-7 | |||
| Name: | Kallikrein-7 | ||
| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 27535.05 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1469257 | ||
| Residue: | 253 | ||
| Sequence: |
| ||
| BDBM100014 | |||
| n/a | |||
| Name | BDBM100014 | ||
| Synonyms: | 4-(3-cyano-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinolin-4-yl)benzoic acid methyl ester | 4-(3-cyano-5-keto-2,7,7-trimethyl-1,4,6,8-tetrahydroquinolin-4-yl)benzoic acid methyl ester | MLS000084922 | SMR000019268 | cid_3239514 | methyl 4-(3-cyano-2,7,7-trimethyl-5-oxidanylidene-1,4,6,8-tetrahydroquinolin-4-yl)benzoate | methyl 4-(3-cyano-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin-4-yl)benzoate | methyl 4-(3-cyano-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinolin-4-yl)benzoate | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H22N2O3 | ||
| Mol. Mass. | 350.411 | ||
| SMILES | COC(=O)c1ccc(cc1)C1C(C#N)C(C)=NC2=C1C(=O)CC(C)(C)C2 |c:16,18| | ||
| Structure | 
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