| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM100087 |
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| Substrate/Competitor | n/a |
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| EC50 | 8200±n/a nM |
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| Citation |  PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM100087 |
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| n/a |
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| Name | BDBM100087 |
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| Synonyms: | (4S)-6-amino-5-cyano-2-(2-keto-2-methoxy-ethyl)-4-(2-nitrophenyl)-4H-pyran-3-carboxylic acid methyl ester | (4S)-6-amino-5-cyano-2-(2-methoxy-2-oxoethyl)-4-(2-nitrophenyl)-4H-pyran-3-carboxylic acid methyl ester | (S)-6-Amino-5-cyano-2-methoxycarbonylmethyl-4-(2-nitro-phenyl)-4H-pyran-3-carboxylic acid methyl ester | MLS000779953 | SMR000420118 | cid_7211646 | methyl (4S)-6-amino-5-cyano-2-(2-methoxy-2-oxoethyl)-4-(2-nitrophenyl)-4H-pyran-3-carboxylate | methyl (4S)-6-azanyl-5-cyano-2-(2-methoxy-2-oxidanylidene-ethyl)-4-(2-nitrophenyl)-4H-pyran-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N3O7 |
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| Mol. Mass. | 373.3169 |
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| SMILES | COC(=O)CC1=C(C([C-](C#N)C(=[NH2+])O1)c1ccccc1[N+]([O-])=O)C(=O)OC |t:5| |
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| Structure | 
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