| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM100189 |
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| Substrate/Competitor | n/a |
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| EC50 | >7722±n/a nM |
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| Citation |  PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM100189 |
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| n/a |
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| Name | BDBM100189 |
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| Synonyms: | 4-[7-(4-carbamoylphenyl)-1-(2-cyclopropyl-2-keto-ethyl)-3-(3,5-dimethoxyphenyl)-1H-isoquinolin-2-yl]benzoic acid methyl ester | 4-[7-(4-carbamoylphenyl)-1-(2-cyclopropyl-2-oxoethyl)-3-(3,5-dimethoxyphenyl)-1H-isoquinolin-2-yl]benzoic acid methyl ester | MLS003591678 | SMR002252975 | cid_53301491 | methyl 4-[7-(4-aminocarbonylphenyl)-1-(2-cyclopropyl-2-oxidanylidene-ethyl)-3-(3,5-dimethoxyphenyl)-1H-isoquinolin-2-yl]benzoate | methyl 4-[7-(4-carbamoylphenyl)-1-(2-cyclopropyl-2-oxoethyl)-3-(3,5-dimethoxyphenyl)-1H-isoquinolin-2-yl]benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C37H34N2O6 |
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| Mol. Mass. | 602.6757 |
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| SMILES | COC(=O)c1ccc(cc1)N1C(CC(=O)C2CC2)c2cc(ccc2C=C1c1cc(OC)cc(OC)c1)-c1ccc(cc1)C(N)=O |c:27| |
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| Structure | 
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