| Reaction Details |
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 | Report a problem with these data |
| Target | Chymase |
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| Ligand | BDBM100312 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Assay |
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| pH | 8±0 |
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| Temperature | 301.15±0 K |
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| IC50 | 3.1±0.0 nM |
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| Citation |  Guo, X; Man, CC; Takahashi, H Azaquinazolinediones chymase inhibitors US Patent US8501749 Publication Date 8/6/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Chymase |
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| Name: | Chymase |
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| Synonyms: | Alpha-chymase | CMA1 | CMA1_HUMAN | CYH | CYM | Chymase precursor | Mast cell protease I |
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| Type: | Enzyme |
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| Mol. Mass.: | 27340.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 247 |
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| Sequence: | MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNF
VLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKA
SLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD
FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWI
NQILQAN
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| BDBM100312 |
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| n/a |
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| Name | BDBM100312 |
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| Synonyms: | US8501749, 12 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H22N4O4 |
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| Mol. Mass. | 454.4773 |
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| SMILES | Cc1cccc2n(C)cc(Cn3c4ccncc4c(=O)n([C@H](C(O)=O)c4ccccc4)c3=O)c12 |r| |
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| Structure | 
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