| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Epoxide hydrolase 1 |
|---|
| Ligand | BDBM100400 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | 87±0.0 nM |
|---|
| Citation |  Hammock, BD; Jones, PD; Morisseau, C; Huang, H; Tsai, H; Gless, Jr., R Conformationally restricted urea inhibitors of soluble epoxide hydrolase US Patent US8501783 Publication Date 8/6/2013 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Epoxide hydrolase 1 |
|---|
| Name: | Epoxide hydrolase 1 |
|---|
| Synonyms: | EPHX | EPHX1 | EPOX | Epoxide hydrolase (EH) | Epoxide hydrolase (HsEH) | Epoxide hydrolase 1 | HYEP_HUMAN | Microsomal epoxide hydrolase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 52954.28 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07099 |
|---|
| Residue: | 455 |
|---|
| Sequence: | MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEI
HDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKI
EGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV
ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVP
SHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYM
HIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVML
YWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKL
ISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ
|
|
|
|---|
| BDBM100400 |
|---|
| n/a |
|---|
| Name | BDBM100400 |
|---|
| Synonyms: | US8501783, 1554 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H19N3O |
|---|
| Mol. Mass. | 257.3309 |
|---|
| SMILES | O=C(NC1CCCCC1)Nc1ccc2[nH]ccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
