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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101665 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 33±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM101665 | |||
| n/a | |||
| Name | BDBM101665 | ||
| Synonyms: | US8530504, 26 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H31N3O4S | ||
| Mol. Mass. | 457.586 | ||
| SMILES | COc1nn2c(csc2c1N(CC1CC1)CC1CCOC1)-c1c(OC)cc(C)cc1OC |(-5.22,-.79,;-4.45,.54,;-2.91,.54,;-2.01,-.7,;-.54,-.23,;.92,-.7,;1.83,.54,;.92,1.79,;-.54,1.31,;-2.01,1.79,;-2.41,3.28,;-3.9,3.68,;-4.29,5.16,;-3.9,6.65,;-5.38,6.25,;-1.32,4.37,;.22,4.37,;1.13,3.12,;2.59,3.6,;2.59,5.14,;1.13,5.61,;1.32,-2.19,;2.81,-2.59,;3.9,-1.5,;5.38,-1.9,;3.2,-4.08,;2.12,-5.16,;2.51,-6.65,;.63,-4.77,;.23,-3.28,;-1.26,-2.88,;-2.35,-3.97,)| | ||
| Structure | 
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