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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101681 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 45±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM101681 | |||
| n/a | |||
| Name | BDBM101681 | ||
| Synonyms: | US8530504, 43 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H33N3O5S | ||
| Mol. Mass. | 475.601 | ||
| SMILES | COCc1cc(OC)c(-c2csc3c(N(CC(C)C)C4CCOC4)c(OC)nn23)c(OC)c1 |(.14,-6.66,;1.62,-7.06,;2.71,-5.97,;2.32,-4.49,;3.4,-3.4,;3.01,-1.91,;4.09,-.82,;5.58,-1.22,;1.52,-1.51,;1.12,-.02,;2.02,1.22,;1.12,2.47,;-.35,1.99,;-1.81,2.47,;-2.21,3.96,;-3.7,4.36,;-4.09,5.84,;-3.01,6.93,;-5.58,6.24,;-1.12,5.05,;.35,4.57,;1.25,5.82,;.35,7.06,;-1.12,6.59,;-2.72,1.22,;-4.26,1.22,;-5.03,-.11,;-1.81,-.02,;-.35,.45,;.43,-2.6,;-1.06,-2.2,;-2.15,-3.29,;.83,-4.09,)| | ||
| Structure | 
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