Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101687 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 59±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM101687 | |||
| n/a | |||
| Name | BDBM101687 | ||
| Synonyms: | US8530504, 49 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H35N3O5S | ||
| Mol. Mass. | 489.628 | ||
| SMILES | COCc1cc(OC)c(-c2csc3c(N(CCOC(C)C)CC4CC4)c(OC)nn23)c(OC)c1 |(6.92,-4.62,;5.83,-5.71,;4.35,-5.31,;3.95,-3.82,;5.04,-2.73,;4.64,-1.25,;5.73,-.16,;7.22,-.56,;3.15,-.85,;2.75,.64,;3.66,1.89,;2.75,3.13,;1.29,2.66,;-.18,3.13,;-.57,4.62,;-2.06,5.02,;-3.15,3.93,;-4.64,4.33,;-5.73,3.24,;-7.22,3.64,;-5.33,1.75,;.51,5.71,;2,5.31,;3.09,4.22,;3.49,5.71,;-1.08,1.89,;-2.62,1.89,;-3.39,.55,;-.18,.64,;1.29,1.12,;2.06,-1.94,;.57,-1.54,;-.51,-2.63,;2.46,-3.42,)| | ||
| Structure | 
| ||