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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101698 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 33±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM101698 | |||
| n/a | |||
| Name | BDBM101698 | ||
| Synonyms: | US8530504, 60 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H33N3O4S | ||
| Mol. Mass. | 483.623 | ||
| SMILES | COc1nn2c(csc2c1N(CC1CC1)CC1CCOC1)-c1c(OC)cc(cc1OC)C1CC1 |(-4.68,.84,;-3.91,2.18,;-2.37,2.18,;-1.46,.93,;,1.41,;1.46,.93,;2.37,2.18,;1.46,3.42,;,2.95,;-1.46,3.42,;-1.86,4.91,;-3.35,5.31,;-4.44,4.22,;-5.93,3.82,;-4.84,2.73,;-.77,6,;.71,5.6,;1.19,4.14,;2.73,4.14,;3.21,5.6,;1.96,6.51,;1.86,-.56,;3.35,-.95,;4.44,.13,;5.93,-.26,;3.75,-2.44,;2.66,-3.53,;1.17,-3.13,;.77,-1.65,;-.71,-1.25,;-1.8,-2.34,;3.06,-5.02,;2.66,-6.51,;4.15,-6.11,)| | ||
| Structure | 
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