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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101699 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 39±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM101699 | |||
| n/a | |||
| Name | BDBM101699 | ||
| Synonyms: | US8530504, 61 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H33N3O4S | ||
| Mol. Mass. | 471.612 | ||
| SMILES | CCCN(C1CCOCC1)c1c(OC)nn2c(csc12)-c1c(OC)cc(cc1OC)C1CC1 |(-5.93,3.58,;-4.44,3.19,;-3.35,4.27,;-1.86,3.88,;-.77,4.96,;.71,4.57,;1.8,5.66,;1.4,7.14,;-.08,7.54,;-1.17,6.45,;-1.46,2.39,;-2.37,1.14,;-3.91,1.14,;-4.68,-.19,;-1.46,-.1,;,.37,;1.46,-.1,;2.37,1.14,;1.46,2.39,;,1.91,;1.86,-1.59,;3.35,-1.99,;4.44,-.9,;5.93,-1.3,;3.75,-3.48,;2.66,-4.57,;1.17,-4.17,;.77,-2.68,;-.71,-2.28,;-1.8,-3.37,;3.06,-6.05,;2.66,-7.54,;4.15,-7.14,)| | ||
| Structure | 
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