| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM103454 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| IC50 | 0.54±0.0 nM |
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| Citation |  Uchikawa, O; Koike, T; Hoashi, Y; Takai, T Tricyclic compound and pharmaceutical use thereof US Patent US8552037 Publication Date 10/8/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM103454 |
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| n/a |
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| Name | BDBM103454 |
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| Synonyms: | US8552037, 116 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N2O3 |
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| Mol. Mass. | 274.315 |
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| SMILES | COc1nc2ccc3CCC(CCNC(C)=O)c3c2o1 |
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| Structure | 
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