| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM103506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | 0.389±0.0 nM |
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| IC50 | 0.837±0.0 nM |
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| Citation |  Ivashchenko, AA; Kysil, VM; Savchuk, NF; Ivashchenko, AV 2-amino-3-sulphonyl-tetrahydro-pyrazolo[1,5-A]pyrido-pyrimidine antagonists of serotonin 5-HT6 receptors, methods for the production and use thereof US Patent US8552017 Publication Date 10/8/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM103506 |
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| n/a |
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| Name | BDBM103506 |
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| Synonyms: | CHEMBL2172186 | US8552017, 1.1(3).HCl |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19N5O2S |
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| Mol. Mass. | 357.43 |
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| SMILES | CNc1nn2c3CCN(C)Cc3cnc2c1S(=O)(=O)c1ccccc1 |
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| Structure | 
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