| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 3 |
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| Ligand | BDBM38239 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FLIPR Assay |
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| IC50 | 319±n/a nM |
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| Citation |  Donello, JE; Beard, RL; Schweighoffer, FJ S1P3 receptor inhibitors for treating pain US Patent US8563594 Publication Date 10/22/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Sphingosine 1-phosphate receptor 3 |
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| Name: | Sphingosine 1-phosphate receptor 3 |
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| Synonyms: | C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42278.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99500 |
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| Residue: | 378 |
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| Sequence: | MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
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| BDBM38239 |
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| n/a |
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| Name | BDBM38239 |
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| Synonyms: | US8563594, 154 | US8563594, Unnumbered 2 |
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| Type | n/a |
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| Emp. Form. | C23H27N2O3P |
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| Mol. Mass. | 410.4458 |
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| SMILES | CCc1ccc(cc1)-c1ccc(CNCCCP(O)(O)=O)nc1-c1ccccc1 |
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| Structure | 
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