Reaction Details |
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Target | P2X purinoceptor 3 |
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Ligand | BDBM106180 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibiton Assay |
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IC50 | 2±n/a nM |
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Citation | Kai, H; Taoda, Y; Endoh, T; Asahi, K; Tobinaga, H Pyrolinone derivative and pharmaceutical composition comprising the same US Patent US8575197 Publication Date 11/5/2013 |
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More Info.: | Get all data from this article, Assay Method |
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P2X purinoceptor 3 |
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Name: | P2X purinoceptor 3 |
Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa |
Type: | Protein |
Mol. Mass.: | 44292.02 |
Organism: | Homo sapiens (Human) |
Description: | P56373 |
Residue: | 397 |
Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
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BDBM106180 |
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n/a |
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Name | BDBM106180 |
Synonyms: | US8575197, II-093 |
Type | Small organic molecule |
Emp. Form. | C27H26N4O2S |
Mol. Mass. | 470.586 |
SMILES | CC(C)c1[nH]nc2C(=O)N(C(c12)c1ccccc1C(=O)N(C)C)c1ccc(cc1)-c1ccsc1 |
Structure |
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