Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2A | ||
| Ligand | BDBM106436 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Radioligand Binding Assay | ||
| Ki | 4.9±0.0 nM | ||
| Citation |  Gobbi, L; Rodriguez Sarmiento, RM; Wichmann, J Anellated pyridine compounds US Patent US8586579 Publication Date 11/19/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 2A | |||
| Name: | 5-hydroxytryptamine receptor 2A | ||
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
| Type: | undefined | ||
| Mol. Mass.: | 52607.65 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28223 | ||
| Residue: | 471 | ||
| Sequence: |
| ||
| BDBM106436 | |||
| n/a | |||
| Name | BDBM106436 | ||
| Synonyms: | US8586579, 25 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H40N4O2S | ||
| Mol. Mass. | 484.697 | ||
| SMILES | CO[C@@H]1CC[C@@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3nccc4sccc34)CC2)C1 |r,wU:10.9,5.5,wD:13.13,2.1,(11.88,-2.45,;10.55,-3.22,;9.22,-2.45,;7.88,-3.22,;6.74,-2.19,;7.37,-.78,;6.6,.55,;5.06,.55,;4.29,-.78,;4.29,1.89,;2.75,1.89,;1.98,.55,;.44,.55,;-.33,1.89,;-1.87,1.89,;-2.64,.55,;-4.18,.55,;-4.95,-.78,;-6.49,-.78,;-7.26,.55,;-6.49,1.89,;-4.95,1.89,;-8.8,.55,;-9.57,1.89,;-11.11,1.89,;-11.88,.55,;-11.11,-.78,;-11.59,-2.25,;-10.34,-3.15,;-9.1,-2.25,;-9.57,-.78,;.44,3.22,;1.98,3.22,;8.9,-.94,)| | ||
| Structure | 
| ||