Ki Summary

Reaction Details

Report a problem with these data

Target

Acetyl-coenzyme A transporter 1

Ligand

BDBM107354

Substrate/Competitor

n/a

Meas. Tech.

Binding Assay

7.4±0

IC50

1.0±0.0 nM

Citation

Maekawa, T; Igawa, H Fused ring compound and use thereof US Patent US8592431 Publication Date 11/26/2013

More Info.:

Get all data from this article, Solution Info, Assay Method

Acetyl-coenzyme A transporter 1

Name:

Acetyl-coenzyme A transporter 1

Synonyms:

ACATN | ACATN_HUMAN | AT1 | Acetyl-coenzyme A transporter 1 (AT1) | SLC33A1

Type:

Enzyme

Mol. Mass.:

60911.27

Organism:

Homo sapiens (Human)

Description:

O00400

Residue:

549

Sequence:

MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
SSWKCKRNN

BDBM107354

n/a

Name

BDBM107354

Synonyms:

US8592431, 147

Type

Small organic molecule

Emp. Form.

C30H32N6O4

Mol. Mass.

540.6129

SMILES

CCCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n(C2CCC(O)CC2)c2ncnn12 |(-6,3.21,;-4.67,2.44,;-3.33,3.21,;-2,2.44,;-.67,3.21,;.67,2.44,;.67,.9,;-.67,.13,;-.67,-1.41,;-2,-2.18,;-3.33,-1.41,;-3.33,.13,;-2,.9,;-4.67,-2.18,;-6,-1.41,;-7.34,-2.18,;-7.34,-3.72,;-6,-4.49,;-4.67,-3.72,;-3.33,-4.49,;-3.33,-6.03,;-1.87,-6.5,;-1.1,-7.83,;-.96,-5.26,;-1.87,-4.01,;2,3.21,;3.33,2.44,;2,4.75,;3.33,5.52,;4.67,4.75,;6,5.52,;6,7.06,;7.34,7.83,;4.67,7.83,;3.33,7.06,;.67,5.52,;.35,7.03,;-1.18,7.19,;-1.81,5.79,;-.67,4.75,)|

Structure