Ki Summary

Reaction Details

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Target

Acetyl-coenzyme A transporter 1

Ligand

BDBM107367

Substrate/Competitor

n/a

Meas. Tech.

Binding Assay

7.4±0

IC50

1.4±0.0 nM

Citation

Maekawa, T; Igawa, H Fused ring compound and use thereof US Patent US8592431 Publication Date 11/26/2013

More Info.:

Get all data from this article, Solution Info, Assay Method

Acetyl-coenzyme A transporter 1

Name:

Acetyl-coenzyme A transporter 1

Synonyms:

ACATN | ACATN_HUMAN | AT1 | Acetyl-coenzyme A transporter 1 (AT1) | SLC33A1

Type:

Enzyme

Mol. Mass.:

60911.27

Organism:

Homo sapiens (Human)

Description:

O00400

Residue:

549

Sequence:

MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
SSWKCKRNN

BDBM107367

n/a

Name

BDBM107367

Synonyms:

US8592431, 168

Type

Small organic molecule

Emp. Form.

C32H34N6O5

Mol. Mass.

582.6496

SMILES

CCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n([C@H]2CC[C@@H](CC2)C(=O)OCC)c2ncnn12 |r,wU:27.29,wD:30.36,(-6.67,1.67,;-5.33,2.44,;-4,1.67,;-2.67,2.44,;-1.33,1.67,;-1.33,.13,;-2.67,-.64,;-2.67,-2.18,;-4,-2.95,;-5.33,-2.18,;-5.33,-.64,;-4,.13,;-6.67,-2.95,;-8,-2.18,;-9.34,-2.95,;-9.34,-4.49,;-8,-5.26,;-6.67,-4.49,;-5.33,-5.26,;-5.33,-6.8,;-3.87,-7.27,;-3.1,-8.6,;-2.96,-6.03,;-3.87,-4.78,;,2.44,;1.33,1.67,;,3.98,;1.33,4.75,;1.33,6.29,;2.67,7.06,;4,6.29,;4,4.75,;2.67,3.98,;5.33,7.06,;5.33,8.6,;6.67,6.29,;8,7.06,;9.34,6.29,;-1.33,4.75,;-1.65,6.26,;-3.19,6.42,;-3.81,5.02,;-2.67,3.98,)|

Structure