Ki Summary

Reaction Details

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Target

Acetyl-coenzyme A transporter 1

Ligand

BDBM107381

Substrate/Competitor

n/a

Meas. Tech.

Binding Assay

7.4±0

IC50

1.6±0.0 nM

Citation

Maekawa, T; Igawa, H Fused ring compound and use thereof US Patent US8592431 Publication Date 11/26/2013

More Info.:

Get all data from this article, Solution Info, Assay Method

Acetyl-coenzyme A transporter 1

Name:

Acetyl-coenzyme A transporter 1

Synonyms:

ACATN | ACATN_HUMAN | AT1 | Acetyl-coenzyme A transporter 1 (AT1) | SLC33A1

Type:

Enzyme

Mol. Mass.:

60911.27

Organism:

Homo sapiens (Human)

Description:

O00400

Residue:

549

Sequence:

MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
SSWKCKRNN

BDBM107381

n/a

Name

BDBM107381

Synonyms:

US8592431, 191

Type

Small organic molecule

Emp. Form.

C31H32N6O4

Mol. Mass.

552.6236

SMILES

CCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n(C2CCC(CC2)=CCO)c2ncnn12 |(-6,2.44,;-4.67,3.21,;-3.33,2.44,;-2,3.21,;-.67,2.44,;-.67,.9,;-2,.13,;-2,-1.41,;-3.33,-2.18,;-4.67,-1.41,;-4.67,.13,;-3.33,.9,;-6,-2.18,;-7.34,-1.41,;-8.67,-2.18,;-8.67,-3.72,;-7.34,-4.49,;-6,-3.72,;-4.67,-4.49,;-4.67,-6.03,;-3.2,-6.5,;-2.43,-7.83,;-2.3,-5.26,;-3.2,-4.01,;.67,3.21,;2,2.44,;.67,4.75,;2,5.52,;3.33,4.75,;4.67,5.52,;4.67,7.06,;3.33,7.83,;2,7.06,;6,7.83,;7.34,7.06,;8.67,7.83,;-.67,5.52,;-.99,7.03,;-2.52,7.19,;-3.14,5.79,;-2,4.75,)|

Structure