| Reaction Details |
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 | Report a problem with these data |
| Target | Cell surface glycoprotein MUC18 |
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| Ligand | BDBM111114 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mushroom Tyrosinase Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 4500±n/a nM |
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| Comments | extracted |
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| Citation |  Nandy, SK; Liu, J; Nesterov, AM; Hertel, C; Papmapiya, AA Series of skin-whitening (lightening) compounds US Patent US9682910 Publication Date 6/20/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell surface glycoprotein MUC18 |
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| Name: | Cell surface glycoprotein MUC18 |
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| Synonyms: | Gicerin | MUC18_MOUSE | Mcam | Melanoma cell adhesion molecule | Melanoma-associated antigen MUC18 | Muc18 |
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| Type: | Protein |
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| Mol. Mass.: | 71536.56 |
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| Organism: | Mouse |
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| Description: | Q8R2Y2 |
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| Residue: | 648 |
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| Sequence: | MGLPKLVCVFLFAACCCCRRAAGVPGEEKQPVPTPDLVEAEVGSTALLKCGPSRASGNFS
QVDWFLIHKERQILIFRVHQGKGQREPGEYEHRLSLQDSVATLALSHVTPHDERMFLCKS
KRPRLQDHYVELQVFKAPEEPTIQANVVGIHVDRQELREVATCVGRNGYPIPQVLWYKNS
LPLQEEENRVHIQSSQIVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNHMKES
KEVTVPVFYPAEKVWVEVEPVGLLKEGDHVTIRCLTDGNPQPHFTINKKDPSTGEMEEES
TDENGLLSLEPAEKHHSGLYQCQSLDLETTITLSSDPLELLVNYVSDVQVNPTAPEVQEG
ESLTLTCEAESNQDLEFEWLRDKTGQLLGKGPVLQLNNVRREAGGRYLCMASVPRVPGLN
RTQLVSVGIFGSPWMALKERKVWVQENAVLNLSCEASGHPQPTISWNVNGSATEWNPDPQ
TVVSTLNVLVTPELLETGAECTASNSLGSNTTTIVLKLVTLTTLIPDSSQTTGLSTLTVS
PHTRANSTSTEKKLPQPESKGVVIVAVIVCTLVLAVLGAALYFFYKKGKLPCGRSGKQEI
TLPPTRKSEFVVEVKSDKLPEEMALLQGSNGDKRAPGDQGEKYIDLRH
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| BDBM111114 |
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| n/a |
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| Name | BDBM111114 |
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| Synonyms: | US9682910, 4-(2-(tetrahydrofuran-2-yl)ethyl)benzene-1,3-diol (25) |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16O3 |
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| Mol. Mass. | 208.2536 |
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| SMILES | Oc1ccc(CCC2CCCO2)c(O)c1 |
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| Structure | 
|
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