| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM108310 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | 0.08±0.0 nM |
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| Citation |  Gao, Z; Hall, D; Hartung, R Substituted piperidine spiro pyrrolidinone and piperidinone, preparation and therapeutic use thereof US Patent US8604046 Publication Date 12/10/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 43426.88 |
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| Organism: | Macaca mulatta (Rhesus macaque) |
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| Description: | G7N499 |
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| Residue: | 390 |
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| Sequence: | MLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDY
LLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGNTRRAVRKMLLVWVLAFLLYGPAILSWE
YLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDG
AREAGGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAAGAEAGETALGGGG
GGGTAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRK
VAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLC
HHSFRRAFTKLLCPQKLKIQPHSSLEQCWK
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| BDBM108310 |
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| n/a |
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| Name | BDBM108310 |
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| Synonyms: | US8604046, 90 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H39FN4O2 |
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| Mol. Mass. | 518.6654 |
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| SMILES | C[C@H]1CCCN1C1CCN(CC1)c1ccc(cc1)N1CCC2(CCN(CC2)C(=O)c2ccc(F)cc2)C1=O |r| |
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| Structure | 
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