Reaction Details | |||
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Target | Serine/threonine-protein kinase pim-1 | ||
Ligand | BDBM108397 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Luminometric Kinase Assay | ||
pH | 7±0 | ||
IC50 | 15.91±0.0 nM | ||
Citation | Brzózka, K; Czardybon, W; Sabiniarz, A; Millik, M; Windak, R; Zarebski, A; Beuzen, N Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent US Patent US8604217 Publication Date 12/10/2013 | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Serine/threonine-protein kinase pim-1 | |||
Name: | Serine/threonine-protein kinase pim-1 | ||
Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) | ||
Type: | Protein | ||
Mol. Mass.: | 35681.82 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P11309 | ||
Residue: | 313 | ||
Sequence: |
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BDBM108397 | |||
n/a | |||
Name | BDBM108397 | ||
Synonyms: | US8604217, 309 | ||
Type | Small organic molecule | ||
Emp. Form. | C13H13Br4N3O | ||
Mol. Mass. | 546.878 | ||
SMILES | OC1CCC(CC1)Nc1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 |(5.5,4.21,;4.73,2.87,;5.5,1.54,;4.73,.21,;3.19,.21,;2.42,1.54,;3.19,2.87,;2.42,-1.13,;.88,-1.13,;-.03,.12,;-1.49,-.36,;-2.83,.41,;-2.83,1.95,;-4.16,-.36,;-5.5,.41,;-4.16,-1.9,;-5.5,-2.67,;-2.83,-2.67,;-2.83,-4.21,;-1.49,-1.9,;-.03,-2.37,)| | ||
Structure |