Reaction Details | |||
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Target | Carboxypeptidase B2 | ||
Ligand | BDBM109264 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Enzyme Inhibition Assay | ||
IC50 | 2.6±n/a nM | ||
Citation | Nagata, T; Inoue, M; Ashida, Y; Noguchi, K; Ono, M Cycloalkyl-substituted imidazole derivative US Patent US8609710 Publication Date 12/17/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Carboxypeptidase B2 | |||
Name: | Carboxypeptidase B2 | ||
Synonyms: | CBPB2_HUMAN | CPB2 | CPU | Carboxypeptidase B2 | Carboxypeptidase B2 isoform A | Carboxypeptidase U | Plasma carboxypeptidase B | TAFI | Thrombin-activable fibrinolysis inhibitor | pCPB | ||
Type: | Enzyme | ||
Mol. Mass.: | 48432.74 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q96IY4 | ||
Residue: | 423 | ||
Sequence: |
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BDBM109264 | |||
n/a | |||
Name | BDBM109264 | ||
Synonyms: | US8609710, 40 | ||
Type | Small organic molecule | ||
Emp. Form. | C16H27N3O2 | ||
Mol. Mass. | 293.4045 | ||
SMILES | C[C@H]1CC[C@@H](CC1)n1cnc(C[C@H](CCCN)C(O)=O)c1 |r,wU:4.7,wD:1.0,12.12,(-6.38,5.14,;-5.98,3.65,;-7.07,2.56,;-6.67,1.07,;-5.18,.68,;-4.09,1.76,;-4.49,3.25,;-4.78,-.81,;-5.69,-2.06,;-4.78,-3.3,;-3.32,-2.83,;-1.98,-3.6,;-.65,-2.83,;-.65,-1.29,;.68,-.52,;.68,1.02,;2.02,1.79,;.68,-3.6,;2.02,-2.83,;.68,-5.14,;-3.32,-1.29,)| | ||
Structure |