| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lipoxygenase |
|---|
| Ligand | BDBM111814 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Lipo-oxygenase activity assay |
|---|
| pH | 7±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 8.951e+4± 9.8e+2 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Ahmad, W; Kumolosasi, E; Jantan, I; Bukhari, SN; Jasamai, M Effects of novel diarylpentanoid analogues of curcumin on secretory phospholipase A2 , cyclooxygenases, lipo-oxygenase, and microsomal prostaglandin E synthase-1. Chem Biol Drug Des83:670-81 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lipoxygenase |
|---|
| Name: | Lipoxygenase |
|---|
| Synonyms: | Lipoxygenase (LOX) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 96302.37 |
|---|
| Organism: | Glycine max (Soybean) |
|---|
| Description: | n/a |
|---|
| Residue: | 859 |
|---|
| Sequence: | MTGGMFGRKGQKIKGTVVLMPKNVLDFNAITSVGKGSAKDTATDFLGKGLDALGHAVDAL
TAFAGHSISLQLISATQTDGSGKGKVGNEAYLEKHLPTLPTLGARQEAFDINFEWDASFG
IPGAFYIKNFMTDEFFLVSVKLEDIPNHGTINFVCNSWVYNFKSYKKNRIFFVNDTYLPS
ATPGPLVKYRQEELEVLRGDGTGKRRDFDRIYDYDIYNDLGNPDGGDPRPIIGGSSNYPY
PRRVRTGREKTRKDPNSEKPGEIYVPRDENFGHLKSSDFLTYGIKSLSQNVIPLFKSIIL
NLRVTSSEFDSFDEVRGLFEGGIKLPTNILSQISPLPVLKEIFRTDGENTLQFPPPHVIR
VSKSGWMTDDEFAREMIAGVNPNVIRRLQEFPPKSTLDPATYGDQTSTITKQQLEINLGG
VTVEEAISAHRLFILDYHDAFFPYLTKINSLPIAKAYATRTILFLKDDGSLKPLAIELSK
PATVSKVVLPATEGVESTIWLLAKAHVIVNDSGYHQLISHWLNTHAVMEPFAIATNRHLS
VLHPIYKLLYPHYKDTININGLARQSLINAGGIIEQTFLPGKYSIEMSSVVYKNWVFTDQ
ALPADLVKRGLAVEDPSAPHGLRLVIEDYPYAVDGLEIWDAIKTWVHEYVSVYYPTNAAI
QQDTELQAWWKEVVEKGHGDLKDKPWWPKLQTVEDLIQSCSIIIWTASALHAAVNFGQYP
YGGYIVNRPTLARRFIPEEGTKEYDEMVKDPQKAYLRTITPKFETLIDISVIEILSRHAS
DEVYLGQRDNPNWTTDSKALEAFKKFGNKLAEIEGKITQRNNDPSLKSRHGPVQLPYTLL
HRSSEEGMSFKGIPNSISI
|
|
|
|---|
| BDBM111814 |
|---|
| n/a |
|---|
| Name | BDBM111814 |
|---|
| Synonyms: | 2,5-Bis[4-(methylaminoethanol)benzylidene] cyclopentanone (13) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H30N2O3 |
|---|
| Mol. Mass. | 406.5173 |
|---|
| SMILES | CNC(CO)c1ccc(\C=C2/CC\C(=C/c3ccc(cc3)C(CO)NC)C2=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
