| Reaction Details |
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 | Report a problem with these data |
| Target | Cytohesin-3 |
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| Ligand | BDBM112784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 40300±n/a nM |
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| Citation |  Degterev, A; Ramana, CV; Miao, B Small molecule antagonists of phosphatidylinositol-3,4,5-triphosphate (PIP3) and uses thereof US Patent US8628961 Publication Date 1/14/2014 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Cytohesin-3 |
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| Name: | Cytohesin-3 |
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| Synonyms: | ARNO3 | CYH3_HUMAN | CYTH3 | GRP1 | General receptor of phosphoinositides 1 (GRP1) | PSCD3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 46340.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43739 |
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| Residue: | 400 |
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| Sequence: | MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYT
TDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYR
ISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
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| BDBM112784 |
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| n/a |
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| Name | BDBM112784 |
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| Synonyms: | US8628961, PIT-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10ClN3O4S |
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| Mol. Mass. | 351.765 |
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| SMILES | Oc1c(Cl)cc(cc1NC(=S)NC(=O)c1ccccc1)[N+]([O-])=O |
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| Structure | 
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